Many allergy sufferers experience frustration when over-the-counter antihistamines fail to provide relief for their nasal and ocular symptoms during allergy season. The reasons include misdiagnosis, varying symptom severity, individual differences, and environmental factors. However, a key factor contributing to the lack of effectiveness of OTC antihistamines is the timing of their usage.
Typically, individuals take antihistamines after allergy symptoms have already manifested. By this point, the body has already released histamine in response to allergens such as pollen, dust mites, mold spores, or animal dander. While antihistamines work to block the action of histamine, they cannot undo the effects of histamine that has already been released. As a result, while these medications can prevent further histamine from causing additional symptoms, they may not fully alleviate existing symptoms.
To improve the effectiveness of antihistamines, some people find it beneficial to take them proactively before allergy symptoms emerge. This approach can help to prevent histamine release in the first place, providing more comprehensive relief. Consulting with a local allergist who can conduct a thorough history, physical examination, and testing is essential for determining the appropriate timing for starting antihistamines preemptively in anticipation of seasonal allergy symptoms.
Raymond Nwadiuko, MD, FACAAI
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